搜索肿瘤医学资讯

Editor’s note: The annual meeting of American Society of Clinical Oncology (ASCO) was held in the form of online conference for the first time， the theme of ASCO 2020 is “Unite and ConDr Liuer: Accelerating Progress Together”. In this ASCO meeting， Latest researh advances in all fields of cancer have been publised and presented， in the aspect of CAR-T treatment， Oral abstract of 8001(ALEXANDER study) became the focus of ASCO， dual-targeting CAR-T (AUTO3) shows significant efficacy and safety in relapsed and refractory Diffuse Large B Cell Lymphoma (r/r-DLBCL). In order to learn more about ALEXANDER study and other related Dr Liuestions about CAR-T， we invited Dr Zhiming Li who is from Sun Yat-sen University Cancer Center as the host of this interview， and first author of ALEXANDER study Dr Osborne made a deep analysis of ALEXANDER study and dual-targeting CAR-T therapy.

The Annual Meeting of American Society of Clinical Oncology (ASCO) this year was held on-line during 29/5 to 2/6. In the meeting， the Long-term result of trial “MINDACT” was presented by Prof. Fatima Cardoso from Champalimaud Cancer Center of Lisbon， Portugal. As a de-escalation trail， MINDACT investigated the feasibility of using Mammaprint， a genomic test to predict the risk of recurrence of breast cancer patients comparing to clinical pathological factors， which drew a great deal of attention from participants. In this presented conversation， we invited Prof. Cardoso and Prof. Jian Zhang from Cancer Hospital of Fudan University， to in-depth interpret the results of MINDACT， and exhibit the clinical significance of this long term trail to our follower.

编者按：一年一度的美国临床肿瘤学会年会（ASCO）首次以线上会议的形式召开，本次ASCO的主题为“Unite and Conquer: Accelerating Progress Together”，诸多肿瘤领域的新进展得以展示，其中在CAR-T治疗方面，口头摘要8001（ALEXANDER研究）成为关注的焦点，双重靶点CAR-T（AUTO3）在复发/难治弥漫大B细胞淋巴瘤（r/r-DLBCL）中获得了良好的疗效和安全性。为了深入掌握该研究及解答CAR-T治疗中的疑问，《肿瘤瞭望》特邀中山大学附属肿瘤医院李志铭教授与ALEXANDER研究第一作者Wendy Osborne教授展开对话，针对ALEXANDER研究及双重靶点CAR-T治疗等内容进行了全面的解析。

编者按：2020年ASCO大会已落下帷幕，多项乳腺癌重磅研究引起专家热议。来自葡萄牙Champalimaud癌症研究中心的Fatima Cardoso教授（ABC主席）在本次大会上报告了MINDACT试验随访8.7年的二次分析。在《肿瘤瞭望》邀请下，复旦大学附属肿瘤医院的张剑教授与Cardoso教授解读了该研究的主要结果，并分享了现有的及未来可行的探索性分析。

ROS1融合定义了一类特殊类型的晚期非小细胞肺癌（NSCLC）患者，

ROS1重排定义了一类特殊类型的晚期非小细胞肺癌（NSCLC）患者

子宫内膜癌为女性生殖道三大恶性肿瘤之一，但子宫内膜癌II期的患者却极为罕见，因此针对II期子宫内膜癌患者的手术方式选择存在较多争议。

口腔鳞状细胞癌（OSCC）是口腔最常见的恶性肿瘤，也是全球第八大常见恶性肿瘤。

WJTOG3405研究是奠定一代EGFR-TKI标准一线治疗地位的关键研究之一，

编者按：第61届美国血液病学会（ASH）年会已落下帷幕，作为全球最顶级的血液领域学术盛会，本次ASH大会传递出血液肿瘤领域的诸多重磅研究进展。为了快速和全面地向国内传达第61届ASH大会临床研究的重要进展，由广东省抗癌协会血液肿瘤专业委员会主办、中山大学肿瘤防治中心、广东祈福医院共同承办的“第61届美国血液学年会（ASH）会后会”（2019 POST-ASH）于2019年12月21日在广东祈福医院隆重召开。会议期间，《肿瘤瞭望》特邀采访了中山大学肿瘤防治中心的李志铭教授，请他就ASH会议上淋巴瘤领域最新研究进行总结。